Reactivation of herpes simplex virus type 1 and varicella-zoster virus and therapeutic effects of combination therapy with prednisolone and valacyclovir in patients with Bell's palsy.

@article{Kawaguchi2007ReactivationOH,
  title={Reactivation of herpes simplex virus type 1 and varicella-zoster virus and therapeutic effects of combination therapy with prednisolone and valacyclovir in patients with Bell's palsy.},
  author={Kazuhiro Kawaguchi and Hiroo Inamura and Yasuhiro Abe and Hidehiro Koshu and Emi Takashita and Yasushi Muraki and Yoko Matsuzaki and Hidekazu Nishimura and Hitoshi Ishikawa and Akira Fukao and Seiji Hongo and Masaru Aoyagi},
  journal={The Laryngoscope},
  year={2007},
  volume={117 1},
  pages={147-56}
}
OBJECTIVES To determine whether reactivation of herpes simplex virus (HSV) type 1 or varicella-zoster virus (VZV) is the main cause of Bell's palsy and whether antiviral drugs bring about recovery from Bell's palsy. STUDY DESIGN Randomized, multicenter, controlled study. METHODS One hundred fifty patients with Bell's palsy were enrolled in this study. The patients were randomly assigned to a prednisolone group or a prednisolone-valacyclovir group, in whom virologic examinations for HSV-1… CONTINUE READING