Reaction site of carboxanilides and of thenoyltrifluoroacetone in complex II.

@article{Ramsay1981ReactionSO,
  title={Reaction site of carboxanilides and of thenoyltrifluoroacetone in complex II.},
  author={Rona R. Ramsay and Brian A. C. Ackrell and Christopher John Coles and Thomas P. Singer and Gordon A. White and G D Thorn},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1981},
  volume={78 2},
  pages={825-8}
}
Oxathiin carboxanilides are systemic fungicides that inhibit the oxidation of succinate by interrupting electron transport between succinate dehydrogenase [succinate:(acceptor) oxidoreductase, EC 1.3.99.1] and coenzyme Q. Kinetic and electron paramagnetic resonance studies have established that the specific binding site of carboxanilides and of thenoyltrifluoroacetone responsible for the inhibition is the same. Although the binding of carboxanilides to membrane preparations of the dehydrogenase… CONTINUE READING

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