Reaction of 2,6-dimethyl-4-hydroxy-5-aminopyrimidine with the vilsmeier reagent

Abstract

Of the described [3] methods for the preparation of pyrrolopyrimidines, one of the most convenient is a method based on the cyclization of substituted 4-methyl-5-aminopyrimidines with the Vilsmeier reagent (VR), which proceeds with the formation of 7-(N,N-dimethylammoniamethylidene)pyrrolo[3,2-c]pyrimidine chloride derivatives [i]. In connection with the… (More)
DOI: 10.1007/BF00776799

Topics

Cite this paper

@article{Sizova2004ReactionO2, title={Reaction of 2,6-dimethyl-4-hydroxy-5-aminopyrimidine with the vilsmeier reagent}, author={Olga S. Sizova and R. G. Glushkov}, journal={Pharmaceutical Chemistry Journal}, year={2004}, volume={18}, pages={420-421} }