Reaction mechanism of oxidative rearrangement of flavanone in isoflavone biosynthesis.

@article{Hashim1990ReactionMO,
  title={Reaction mechanism of oxidative rearrangement of flavanone in isoflavone biosynthesis.},
  author={Mir Hashim and Takashi Hakamatsuka and Yutaka Ebizuka and Ushio Sankawa},
  journal={FEBS letters},
  year={1990},
  volume={271 1-2},
  pages={219-22}
}
Microsomes that were prepared from elicitor-treated Pueraria lobata cell cultures catalyzed the conversion of liquiritigenin, a flavanone, into daidzein, an isoflavone. The reaction was resolved into two steps. 2, 7, 4'-Trihydroxyisoflavonone was formed as a major product when liquiritigenin was incubated with carefully washed microsomes in the presence of NADPH. The structure of 2, 7, 4'-trihydroxyisoflavanone was confirmed by mass and 1H NMR spectroscopies. The enzyme responsible for this… CONTINUE READING
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Cytochrome P-450, Structure, Mechanism and Biochemistry (Ortiz de Montellano, P.R. ed) pp. l-28

  • T. J. McMurry, J. T. Groves
  • 1986

The Flavonoids, Advances in Research (Harborne

  • P. M. Dewick
  • J.B. and Mabry, T.J. eds) pp
  • 1982

Biochemistry and Chemistry of Planr Growth Regulator5 (Schreiber

  • J. E. Graebe, P. Hedden
  • I<., Schutte, H.R. and Sembdner. G. eds) pp. l-16…
  • 1974

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