Reaction kinetic analysis of the 3-hydroxypropionate/4-hydroxybutyrate CO2 fixation cycle in extremely thermoacidophilic archaea.

@article{Loder2016ReactionKA,
  title={Reaction kinetic analysis of the 3-hydroxypropionate/4-hydroxybutyrate CO2 fixation cycle in extremely thermoacidophilic archaea.},
  author={A. Loder and Y. Han and Aaron B Hawkins and H. Lian and G. L. Lipscomb and G. Schut and Matthew W. Keller and M. Adams and R. Kelly},
  journal={Metabolic engineering},
  year={2016},
  volume={38},
  pages={
          446-463
        }
}
  • A. Loder, Y. Han, +6 authors R. Kelly
  • Published 2016
  • Biology, Medicine
  • Metabolic engineering
  • The 3-hydroxypropionate/4-hydroxybutyrate (3HP/4HB) cycle fixes CO2 in extremely thermoacidophilic archaea and holds promise for metabolic engineering because of its thermostability and potentially rapid pathway kinetics. A reaction kinetics model was developed to examine the biological and biotechnological attributes of the 3HP/4HB cycle as it operates in Metallosphaera sedula, based on previous information as well as on kinetic parameters determined here for recombinant versions of five of… CONTINUE READING
    9 Citations
    Enzymes Catalyzing Crotonyl-CoA Conversion to Acetoacetyl-CoA During the Autotrophic CO2 Fixation in Metallosphaera sedula
    • Highly Influenced
    • PDF
    Biotechnology of extremely thermophilic archaea.
    • 16
    • PDF
    Extremely thermophilic energy metabolisms: biotechnological prospects.
    • 14
    • PDF
    Engineering Microorganisms for Enhanced CO2 Sequestration.
    • 5
    The renaissance of life near the boiling point – at last, genetics and metabolic engineering
    • 5
    • PDF

    References

    SHOWING 1-10 OF 59 REFERENCES
    3-hydroxypropionyl-coenzyme A dehydratase and acryloyl-coenzyme A reductase, enzymes of the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle in the Sulfolobales.
    • 57
    • Highly Influential
    • PDF
    3-Hydroxypropionyl-coenzyme A synthetase from Metallosphaera sedula, an enzyme involved in autotrophic CO2 fixation.
    • 38
    • Highly Influential
    • PDF
    A 3-Hydroxypropionate/4-Hydroxybutyrate Autotrophic Carbon Dioxide Assimilation Pathway in Archaea
    • 447
    • PDF
    Malonyl-coenzyme A reductase in the modified 3-hydroxypropionate cycle for autotrophic carbon fixation in archaeal Metallosphaera and Sulfolobus spp.
    • 81
    • Highly Influential
    • PDF
    Role of 4-Hydroxybutyrate-CoA Synthetase in the CO2 Fixation Cycle in Thermoacidophilic Archaea*
    • 22
    • PDF
    Characterization of acetyl-CoA/propionyl-CoA carboxylase in Metallosphaera sedula. Carboxylating enzyme in the 3-hydroxypropionate cycle for autotrophic carbon fixation.
    • 92
    • Highly Influential
    Study of the distribution of autotrophic CO2 fixation cycles in Crenarchaeota.
    • 75
    • Highly Influential
    • PDF
    A dicarboxylate/4-hydroxybutyrate autotrophic carbon assimilation cycle in the hyperthermophilic Archaeum Ignicoccus hospitalis
    • 201
    • PDF