Reaction-diffusion in complex 3D geometries: mesh construction and stochastic simulation with STEPS

@article{Wils2008ReactiondiffusionIC,
  title={Reaction-diffusion in complex 3D geometries: mesh construction and stochastic simulation with STEPS},
  author={Stefan Wils and Erik De Schutter},
  journal={BMC Neuroscience},
  year={2008},
  volume={9},
  pages={1-1}
}
Computational modeling and simulation of signaling pathways has become a valuable and established tool for studying the molecular aspects of biological systems. Aside from the reaction kinetics themselves, the spatial organization and morphology of the cell is known to play an active role in many of these pathways through chemical compartmentalization and by various transport processes. The first step towards simulating these morphological aspects, therefore, is to construct a computational… CONTINUE READING