Reactant and Waste Minimization in Multitarget Sample Preparation on Digital Microfluidic Biochips

@article{Huang2013ReactantAW,
  title={Reactant and Waste Minimization in Multitarget Sample Preparation on Digital Microfluidic Biochips},
  author={Juinn-Dar Huang and C. Liu and Huei-Shan Lin},
  journal={IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems},
  year={2013},
  volume={32},
  pages={1484-1494}
}
  • Juinn-Dar Huang, C. Liu, Huei-Shan Lin
  • Published 2013
  • Computer Science
  • IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
  • Sample preparation is one of essential processes in biochemical reactions. Raw reactants are diluted in this process to achieve given target concentrations. A bioassay may require several different target concentrations of a reactant. Both the dilution operation count and the reactant usage can be minimized if multiple target concentrations are considered simultaneously during sample preparation. Hence, in this paper, we propose a multitarget sample preparation algorithm that extensively… CONTINUE READING

    Figures and Topics from this paper.

    Explore Further: Topics Discussed in This Paper

    Sample preparation for many-reactant bioassay on DMFBs using common dilution operation sharing
    • 28
    Recent Advances in Applications of Droplet Microfluidics
    • 77
    • Open Access
    Reactant Minimization in Sample Preparation on Digital Microfluidic Biochips
    • 18
    An open-source compiler and PCB synthesis tool for digital microfluidic biochips
    • 42
    • Highly Influenced
    • Open Access
    Theory and analysis of generalized mixing and dilution of biochemical fluids using digital microfluidic biochips
    • 17
    • Highly Influenced

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 37 REFERENCES
    Electrowetting-based actuation of liquid droplets for microfluidic applications
    • 1,167
    • Open Access
    Rapid droplet mixers for digital microfluidic systems.
    • 438
    • Open Access
    Chemical and Biological Applications of Digital-Microfluidic Devices
    • 265
    • Open Access
    On-chip biochemical sample preparation using digital microfluidics
    • 26