Reabsorption and intracellular transport of cytochrome c and lysozyme in rat kidney.


Renal uptake and degradation of cytochrome c and lysozyme were investigated, using preparations that were labelled by means of covalent coupling of either protein to iodinated tyramine-cellobiose. Following proteolytic digestion, the label remains 'trapped' within intracellular organelles. Within 15 min after intravenous injection, 43% of the [125I]tyramine… (More)


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