[Re-expression of p16 gene in myeloma cell line U266 by arsenic trioxide].

Abstract

BACKGROUND & OBJECTIVE DNA methylation status regulates gene expression and is associated with oncogenesis. Demethylation of DNA has been proposed as a possible new strategy for cancer prophylaxis and treatment. S-adenosylmethionine is required as methyl donor for both arsenic metabolism and DNA methylation. The present study was designed to explore the… (More)

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@article{Li2004ReexpressionOP, title={[Re-expression of p16 gene in myeloma cell line U266 by arsenic trioxide].}, author={Jin-qing Li and Yuan Li and Yong-jin Shi and Shu-lan Wu}, journal={Ai zheng = Aizheng = Chinese journal of cancer}, year={2004}, volume={23 6}, pages={626-30} }