Re-examination of the lymphocytotoxic crossmatch in liver transplantation: can C4d stains help in monitoring?

@article{Lunz2012ReexaminationOT,
  title={Re-examination of the lymphocytotoxic crossmatch in liver transplantation: can C4d stains help in monitoring?},
  author={John G. Lunz and K Ruppert and Mariana M Cajaiba and Kumiko Isse and Carol A Bentlejewski and Marta Ida Minervini and Michael Andrew Nalesnik and Parmjeet A Randhawa and Erin Rubin and Eisaburo Sasatomi and Michael E. de Vera and Paulo Fontes and Atul Humar and Adriana Zeevi and Anthony Jake Demetris},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2012},
  volume={12 1},
  pages={171-82}
}
C4d-assisted recognition of antibody-mediated rejection (AMR) in formalin-fixed paraffin-embedded tissues (FFPE) from donor-specific antibody-positive (DSA+) renal allograft recipients prompted study of DSA+ liver allograft recipients as measured by lymphocytotoxic crossmatch (XM) and/or Luminex. XM results did not influence patient or allograft survival, or cellular rejection rates, but XM+ recipients received significantly more prophylactic steroids. Endothelial C4d staining strongly… CONTINUE READING
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Clinical and histological predictors of operational tolerance in pediatric liver transplant recipients

  • S Feng, U Ekong, S Lobritto
  • Am J Transplant
  • 2011
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