Re-evaluation of the effects of neuropeptide Y on aggregation of human platelets.

  title={Re-evaluation of the effects of neuropeptide Y on aggregation of human platelets.},
  author={A. Myers and S. Abi-Younes and Z. Żukowska-Gr{\'o}jec},
  journal={Life sciences},
  volume={49 7},
  • A. Myers, S. Abi-Younes, Z. Żukowska-Grójec
  • Published 1991
  • Chemistry, Medicine
  • Life sciences
  • Several studies have shown that platelets are a major source of circulating neuropeptide Y (NPY) immunoreactivity in rats, but the effects of this vasoconstrictor peptide on platelets are not well-defined. Recently, it was reported that porcine NPY was an inhibitor of in vitro human platelet aggregation induced by epinephrine, an observation which would have important implications regarding platelet-vascular interactions during states involving platelet activation and thrombosis. Thus, we… CONTINUE READING
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