Re-evaluation of mammary stem cell biology based on in vivo transplantation

  title={Re-evaluation of mammary stem cell biology based on in vivo transplantation},
  author={Gilbert H Smith and Daniel J. Medina},
  journal={Breast Cancer Research : BCR},
  pages={203 - 203}
Over nearly half a century, transplantation methods have been employed to regenerate the mammary gland in vivo. Recent highly cited reports claim to have demonstrated the regeneration of an entire functional mammary gland from a single mammary epithelial cell. Nevertheless, re-examination of the literature on the transplantation biology of mammary gland regeneration reveals that a complex, combinatorial interaction between variously differentiated mammary epithelial cells and the mammary fat… CONTINUE READING

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