Re-evaluation of gonadotropin-releasing hormone (GnRH) action on pituitary cell differentiation with special regard to its effect on LH and TSH cell types.

@article{Hritier1994ReevaluationOG,
  title={Re-evaluation of gonadotropin-releasing hormone (GnRH) action on pituitary cell differentiation with special regard to its effect on LH and TSH cell types.},
  author={Adriennne H{\'e}ritier and Paul-M. Dubois},
  journal={Journal of neuroendocrinology},
  year={1994},
  volume={6 1},
  pages={
          33-7
        }
}
We have previously demonstrated that TRH induces several hypophyseal cell type differentiation. In the present study, we re-evaluated the effect of GnRH on gonadotroph differentiation, and we determined whether gonadotropin is implicated in the appearance of other pituitary cell types. These effects were compared to the influence of TRH on LH and TSH cell differentiation. Pituitary primordia of 11 day-old rat embryos were cultured in a synthetic medium until the equivalent of term, and the LH… CONTINUE READING
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