Re-emergence of Lloviu virus in Miniopterus schreibersii bats, Hungary, 2016

@article{Kemenesi2018ReemergenceOL,
  title={Re-emergence of Lloviu virus in Miniopterus schreibersii bats, Hungary, 2016},
  author={G{\'a}bor Kemenesi and Korn{\'e}lia Kurucz and Bianka Dallos and Brigitta Zana and Fanni F{\"o}ldes and S{\'a}ndor Andr{\'a}s Boldogh and Tam{\'a}s G{\"o}rf{\"o}l and Miles W. Carroll and Ferenc Jakab},
  journal={Emerging Microbes \& Infections},
  year={2018},
  volume={7}
}
Members of the virus family Filoviridae, such as ebola viruses and marburgviruses, cause hemorrhagic fevers associated with high mortality and are, therefore, of major public health importance worl... 
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Lleida Bat Lyssavirus isolation in Miniopterus schreibersii in France
TLDR
The analysis of the complete genome sequence confirmed the presence of Lleida bat lyssavirus (LLEBV) in bats in France with 99.7% of nucleotide identity with the Spanish LLEbV strain (KY006983).
Lloviu Virus in Europe is an Emerging Disease of Concern
TLDR
The presence of the Lloviu filovirus in dead animals from January of 2019 and living bats in autumn 2019 at one previously affected roost in Hungary presented evidence for the continuous circulation of LLOV there, and the zoonotic potential of the virus was confirmed.
Reservoir host studies of Lloviu virus: first isolation, sequencing and serology in Schreiber’s bats in Europe
TLDR
The role of bats, specifically Miniopterus schreibersii as natural reservoirs for the LLOV filovirus in Europe is supported and bat-associated parasites might play a role in the natural ecology of filoviruses in temperate climate regions compared to filovIRuses in the tropics.
Update on Potentially Zoonotic Viruses of European Bats
TLDR
The present review provides an update on the earlier article and summarizes the most important viruses found in European bats and their possible implications for Public Health.
Characterization of a filovirus (Měnglà virus) from Rousettus bats in China
TLDR
The characterization of a phylogenetically distinct bat filovirus, named Měnglà virus (MLAV), whose genome shares 32–54% nucleotide sequence identity with known filoviruses, indicates a broad species cell tropism with a high risk of interspecies spillover transmission.
Assessment of the function and intergenus-compatibility of Ebola and Lloviu virus proteins.
TLDR
It is shown that all LLOV proteins fulfill their canonical role in the virus life cycle as expected based on the well-studied related filovirus Ebola virus, and some but not all proteins from LLOV and Ebola virus are compatible with each other.
Serological Evidence for Henipa-like and Filo-like Viruses in Trinidad Bats.
Bat-borne zoonotic pathogens belonging to the family Paramxyoviridae, including Nipah and Hendra viruses, and the family Filoviridae, including Ebola and Marburg viruses, can cause severe disease and…
Isolation of infectious Lloviu virus from Schreiber’s bats in Hungary
TLDR
The role of bats, specifically Miniopterus schreibersii as hosts for LLOV in Europe is supported and it is suggested that bat-associated parasites might play a role in the natural ecology of filoviruses in temperate climate regions compared to filovIRuses in the tropics.
Filovirus infection induces an anti-inflammatory state in Rousettus bats
TLDR
Novel transcriptional pathways that suggest infected bats exhibit impaired coagulation, vasodilation, aberrant iron regulation, and impaired complement system leading to muted antibody responses are identified, which likely control infection and limit pathology.
Filiviruses of southeast Asia, China and Europe (review)
TLDR
Data is summarized on findings of filovirus markers in animals in Southeast Asia, China and Europe to indicate the possibility of circulation offiloviruses with unknown pathogenicity potential for humans and animals among bats of temperate latitudes.
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References

SHOWING 1-10 OF 17 REFERENCES
Discovery of an Ebolavirus-Like Filovirus in Europe
Filoviruses, amongst the most lethal of primate pathogens, have only been reported as natural infections in sub-Saharan Africa and the Philippines. Infections of bats with the ebolaviruses and…
Genetically Diverse Filoviruses in Rousettus and Eonycteris spp. Bats, China, 2009 and 2015
TLDR
Results demonstrate that fruit bats are key reservoirs of filoviruses, based on partial replicase sequences, and demonstrate lung tropism.
Filovirus RNA in Fruit Bats, China
TLDR
A study to investigate the presence of filoviruses in bats in China found positive amplification in specimens from its lung but not from intestine, liver, or brain tissue, and designed and reassembled de novo 10 million reads into 590,010 contigs.
Marburg- and Ebolaviruses
TLDR
The desperate hunt of the causative agent of this first filovirus disease outbreak in the center of Europe, its successful isolation, the likely route of transmission from a monkey trading station to vaccine production facilities in Germany and Yugoslavia, and the consequences of this outbreak, including a shortage in the production of poliomyelitis vaccine are described.
Neglected filoviruses.
TLDR
This review summarizes the current knowledge on less well-characterized filoviruses, including Bundibugyo virus, Lloviu virus, Ravn virus, Reston virus and Taï Forest virus, and investigates the possibility of the future occurrence of a large disease outbreak caused by other less characterized filovIRuses.
Comprar Marburg- and Ebolaviruses. From Ecosystems to Molecules (Current Topics in Microbiology and Immunology, Vol. 411) | Elke Mühlberger | 9783319689463 | Springer
TLDR
From Ecosystems to Molecules (Current Topics in Microbiology and Immunology, Vol. 411) al precio 161,50 € de Elke Muhlberger | Lisa L. Hensley | Jonathan S. Towner.
An Emerging Disease Causes Regional Population Collapse of a Common North American Bat Species
TLDR
It seems that although rabies viruses have the potential for rapid evolution, this property alone is not enough to overcome genetic barriers, which inhibit the onward transmission of rabies virus into a new species.
Characterization of the Envelope Glycoprotein of a Novel Filovirus, Lloviu Virus
TLDR
Interestingly, LLOV GP-pseudotyped VSV infected particular bat cell lines more efficiently than viruses bearing other filovirus GPs, suggesting that LLOV mediates cellular entry in a manner similar to that of the otherfiloviruses while showing preferential tropism for some bat cells.
Marburg and Ebola viruses.
Cell entry by a novel European filovirus requires host endosomal cysteine proteases and Niemann-Pick C1.
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