Re-creating an RNA world

@article{Mller2006RecreatingAR,
  title={Re-creating an RNA world},
  author={Ulrich F. M{\"u}ller},
  journal={Cellular and Molecular Life Sciences CMLS},
  year={2006},
  volume={63},
  pages={1278-1293}
}
  • U. F. Müller
  • Published 2 May 2006
  • Biology
  • Cellular and Molecular Life Sciences CMLS
Abstract.The RNA world hypothesis states that life originated via a system based on RNA genomes and RNA catalysts. Researchers have been trying to develop such a system since catalytic RNAs (ribozymes) were discovered in 1982. This review summarizes the recent progress made in that endeavor and outlines the obstacles that remain to be overcome. After giving a short background on prebiotic chemistry and in vitro evolution, the discussion focuses on the generation of three important components of… 

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