Re: Epigenetic disruption of the PIWI pathway in human spermatogenic disorders.


Epigenetic changes are involved in a wide range of common human diseases. Although DNA methylation defects are known to be associated with male infertility in mice, their impact on human deficiency of sperm production has yet to be determined. We have assessed the global genomic DNA methylation profiles in human infertile male patients with spermatogenic… (More)
DOI: 10.1016/j.juro.2013.02.3213


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