Rbs1, a New Protein Implicated in RNA Polymerase III Biogenesis in Yeast Saccharomyces cerevisiae

@article{Ciesla2015Rbs1AN,
  title={Rbs1, a New Protein Implicated in RNA Polymerase III Biogenesis in Yeast Saccharomyces cerevisiae},
  author={Małgorzata Cieśla and Ewa Makała and Marta Płonka and Rafał Bazan and Kamil Gewartowski and Andrzej Dziembowski and Magdalena Boguta},
  journal={Molecular and Cellular Biology},
  year={2015},
  volume={35},
  pages={1169 - 1181}
}
ABSTRACT Little is known about the RNA polymerase III (Pol III) complex assembly and its transport to the nucleus. We demonstrate that a missense cold-sensitive mutation, rpc128-1007, in the sequence encoding the C-terminal part of the second largest Pol III subunit, C128, affects the assembly and stability of the enzyme. The cellular levels and nuclear concentration of selected Pol III subunits were decreased in rpc128-1007 cells, and the association between Pol III subunits as evaluated by… 
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