RbfA from 30 S ribosome during a late stage of ribosome biosynthesis

  title={RbfA from 30 S ribosome during a late stage of ribosome biosynthesis},
  author={Simon Goto and Shingo Kato and Takatsugu Kimura and Akira Muto and Hyouta Himeno},
RsgA is a 30S ribosomal subunit-binding GTPase with an unknown function, shortage of which impairs maturation of the 30S subunit. We identified multiple gain-of-function mutants of Escherichia coli rbfA, the gene for a ribosomebinding factor, that suppress defects in growth and maturation of the 30S subunit of an rsgA-null strain. These mutations promote spontaneous release of RbfA from the 30S subunit, indicating that cellular disorders upon depletion of RsgA are due to prolonged retention of… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 61 references

The weird and wonderful world of bacterial ribosome regulation.

Critical reviews in biochemistry and molecular biology • 2007
View 4 Excerpts
Highly Influenced

Era and RbfA have overlapping function in ribosome biogenesis in Escherichia coli.

Journal of molecular microbiology and biotechnology • 2006
View 10 Excerpts
Highly Influenced

Driving ribosome assembly.

Biochimica et biophysica acta • 2010
View 1 Excerpt

Deconstructing ribosome construction.

Trends in biochemical sciences • 2009
View 2 Excerpts

Similar Papers

Loading similar papers…