Rb loss is characteristic of prostatic small cell neuroendocrine carcinoma.

Abstract

PURPOSE Small cell neuroendocrine carcinoma of the prostate is likely to become increasingly common with recent advances in pharmacologic androgen suppression. Thus, developing molecular markers of small cell differentiation in prostate cancer will be important to guide the diagnosis and therapy of this aggressive tumor. EXPERIMENTAL DESIGN We examined… (More)
DOI: 10.1158/1078-0432.CCR-13-1982

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