Rattlesnake presynaptic neurotoxins: primary structure and evolutionary origin of the acidic subunit.

@article{Aird1985RattlesnakePN,
  title={Rattlesnake presynaptic neurotoxins: primary structure and evolutionary origin of the acidic subunit.},
  author={Steven D Aird and I I. Kaiser and Randolph V Lewis and W G Kruggel},
  journal={Biochemistry},
  year={1985},
  volume={24 25},
  pages={7054-8}
}
Crotoxin and homologous crotalid presynaptic neurotoxins consist of a toxic, basic subunit and a slightly smaller, nontoxic, acidic subunit. The latter, in turn, consists of three chains, interconnected by disulfide bonds. The complete sequences of two of the three acidic subunit chains of crotoxin, from the venom of the South American rattlesnake Crotalus durissus terrificus, have been determined. In addition, all but the ten amino-terminal residues of the third chain have been sequenced… CONTINUE READING

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