Rationale for using serotonergic agents to treat irritable bowel syndrome.

  title={Rationale for using serotonergic agents to treat irritable bowel syndrome.},
  author={Danial E. Baker},
  journal={American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists},
  volume={62 7},
  pages={700-11; quiz 712-3}
  • Danial E. Baker
  • Published 2005 in
    American journal of health-system pharmacy : AJHP…
PURPOSE The role of serotonin in gastrointestinal (GI)-tract functioning, the pharmacologic rationale for using serotonergic agents in the treatment of irritable bowel syndrome (IBS), and clinical experience with novel serotonergic agents are described. SUMMARY IBS is a common multisymptom disorder that is associated with a high socioeconomic burden. The goal of treatment is to provide rapid and sustained global relief of the multiple symptoms of IBS with a single, effective, well-tolerated… CONTINUE READING


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