Rationale and design of the LURIC study--a resource for functional genomics, pharmacogenomics and long-term prognosis of cardiovascular disease.

@article{Winkelmann2001RationaleAD,
  title={Rationale and design of the LURIC study--a resource for functional genomics, pharmacogenomics and long-term prognosis of cardiovascular disease.},
  author={Bernhard Rudolf Winkelmann and Winfried Maerz and B O Boehm and Rainer Zotz and J{\"o}rg Hager and Peter Hellstern and Jochen Senges},
  journal={Pharmacogenomics},
  year={2001},
  volume={2 1 Suppl 1},
  pages={S1-73}
}
BACKGROUND AND AIM Coronary artery disease (CAD), arterial hypertension and Type 2 diabetes mellitus are common polygenetic disorders which have a major impact on public health. Disease prevalence and progression to cardiovascular complications, such as myocardial infarction (MI), stroke or heart failure, are the product of environment and gene interaction. The LUdwigshafen RIsk and Cardiovascular Health (LURIC) study aims to provide a well-defined resource for the study of environmental and… CONTINUE READING

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