Rationale and design of INTERSTROKE: a global case-control study of risk factors for stroke.

@article{ODonnell2010RationaleAD,
  title={Rationale and design of INTERSTROKE: a global case-control study of risk factors for stroke.},
  author={Martin J O'Donnell and Denis Xavier and Christoph Diener and Ralph I Sacco and Liu Lisheng and Hong-Yu Zhang and Paola Pias and Thomas Truelsen and Sophie L Chin and Sumathy Rangarajan and Laetitia Devilliers and Alfredo Damasceno and Charles Kiiza Mondo and Fernando Lanas and Alvaro A Avezum and Rafael D{\'i}az and John D Varigos and Graeme J. Hankey and Philip Teal and Moira K. Kapral and Danuta Krystyna Ryglewicz and Anna Czlonkowska and Marta Skowronska and Patricio L{\'o}pez-Jaramillo and Tony Dans and Peter Langhorne and Salim Yusuf},
  journal={Neuroepidemiology},
  year={2010},
  volume={35 1},
  pages={36-44}
}
UNLABELLED Stroke is a major global health problem. It is the third leading cause of death and the leading cause of adult disability. INTERHEART, a global case-control study of acute myocardial infarction in 52 countries (29,972 participants), identified nine modifiable risk factors that accounted for >90% of population-attributable risk. However, traditional risk factors (e.g. hypertension, cholesterol) appear to exert contrasting risks for stroke compared with coronary heart disease, and the… CONTINUE READING