Rationale, mechanisms of efficacy, anatomical targets and future prospects of electrical deep brain stimulation for epilepsy.

@article{Pollo2007RationaleMO,
  title={Rationale, mechanisms of efficacy, anatomical targets and future prospects of electrical deep brain stimulation for epilepsy.},
  author={Claudio Pollo and Jean Guy Villemure},
  journal={Acta neurochirurgica. Supplement},
  year={2007},
  volume={97 Pt 2},
  pages={311-20}
}
Electrical stimulation of deep brain structures is a promising new technology for the treatment of medically intractable seizures. Performed in vitro and on animal models of epilepsy, electrical stimulation has shown to reduce seizure frequency. Preliminary results on humans are encouraging. However, such improvements emerge despite a lack of understanding of the precise mechanisms underlying electrical stimulation either delivered directly on the epileptogenic zone (direct control) or through… CONTINUE READING
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