Rational use of new and existing disease-modifying agents in rheumatoid arthritis.

@article{Kremer2001RationalUO,
  title={Rational use of new and existing disease-modifying agents in rheumatoid arthritis.},
  author={Joel M. Kremer},
  journal={Annals of internal medicine},
  year={2001},
  volume={134 8},
  pages={
          695-706
        }
}
Rheumatoid arthritis is a disease with considerable individual and societal costs (1-5). Disability is common (6, 7) and often occurs quickly (4, 5). Radiographic progression can also be rapid (8-10) and may be inexorable over the course of decades (11). Mortality rates increase in patients with severe continuing disease (7, 12). However, it is becoming increasingly clear that deformity, disability, and death may be avoided when newly approved and existing disease-modifying antirheumatic drugs… CONTINUE READING
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Limits of add-on trials: antirheumatic drugs

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  • Zeitschrift für Rheumatologie
  • 2015
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