Rational design of smart supramolecular assemblies for gene delivery: chemical challenges in the creation of artificial viruses.

Abstract

Polymeric materials have been extensively developed as a delivery vehicle for nucleic acids over the past two decades. Many previous studies have demonstrated that synthetic delivery vehicles can be highly functionalized by chemical approaches to overcome biological barriers in nucleic acid delivery, similar to viruses. Based on our current knowledge, this… (More)
DOI: 10.1039/c1cs15258k

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