Rational assignment of key motifs for function guides in silico enzyme identification.

Abstract

Biocatalysis has emerged as a powerful alternative to traditional chemistry, especially for asymmetric synthesis. One key requirement during process development is the discovery of a biocatalyst with an appropriate enantiopreference and enantioselectivity, which can be achieved, for instance, by protein engineering or screening of metagenome libraries. We… (More)
DOI: 10.1038/nchembio.447

Topics

Cite this paper

@article{Hhne2010RationalAO, title={Rational assignment of key motifs for function guides in silico enzyme identification.}, author={Matthias H{\"o}hne and Sebastian Sch{\"a}tzle and Helge Jochens and Karen Robins and Uwe T Bornscheuer}, journal={Nature chemical biology}, year={2010}, volume={6 11}, pages={807-13} }