Rational antibiotic therapy and the position of ampicillin/sulbactam.

  title={Rational antibiotic therapy and the position of ampicillin/sulbactam.},
  author={Hartmut M Lode},
  journal={International journal of antimicrobial agents},
  volume={32 1},
In the current context of increasing antimicrobial resistance, it is important to use antibiotics rationally and to re-assess regularly the clinical usefulness of commonly used agents. This review focuses on the efficacy of the beta-lactam ampicillin co-administered with the beta-lactamase inhibitor sulbactam, either parenterally (ampicillin/sulbactam) or orally (sultamicillin), for the treatment of bacterial infections. Clinical findings from the past decade confirm the results of numerous… CONTINUE READING


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