Rational Design of Multifunctional Dendritic Mesoporous Silica Nanoparticles to Load Curcumin and Enhance Efficacy for Breast Cancer Therapy.

@article{Wang2016RationalDO,
  title={Rational Design of Multifunctional Dendritic Mesoporous Silica Nanoparticles to Load Curcumin and Enhance Efficacy for Breast Cancer Therapy.},
  author={Jiao Wang and Yue Wang and Qiang Liu and Linnan Yang and Rongrong Zhu and Chengzhong Yu and Shilong Wang},
  journal={ACS applied materials & interfaces},
  year={2016},
  volume={8 40},
  pages={
          26511-26523
        }
}
Breast cancer is the primary reason for cancer-related death in women worldwide and the development of new formulations to treat breast cancer patients is crucial. Curcumin (Cur), a natural product, exerts promising anticancer activities against various cancer types. However, its therapeutic efficacy is hindered as a result of poor water solubility, instability, and low bioavailability. The aim of this work is to assess the curative effect of a novel nanoformulation, i.e., Cur-loaded and… CONTINUE READING
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