Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

@article{Wu2010RationalDO,
  title={Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1},
  author={Xueling Wu and Zhi-Yong Yang and Yuxing Li and Carl-Magnus Hogerkorp and William R. Schief and Michael S. Seaman and Tongqing Zhou and Stephen D. Schmidt and Lan Wu and Ling Xu and Nancy S. Longo and K Mckee and Sijy O'dell and Mark K. Louder and Diane L Wycuff and Yu Feng and Martha C. Nason and Nicole A. Doria-Rose and Mark Connors and Peter D. Kwong and Mario Roederer and Richard T. Wyatt and Gary J. Nabel and John R. Mascola},
  journal={Science},
  year={2010},
  volume={329},
  pages={856 - 861}
}
Designer Anti-HIV Developing a protective HIV vaccine remains a top global health priority. One strategy to identify potential vaccine candidates is to isolate broadly neutralizing antibodies from infected individuals and then attempt to elicit the same antibody response through vaccination (see the Perspective by Burton and Weiss). Wu et al. (p. 856, published online 8 July) now report the identification of three broadly neutralizing antibodies, isolated from an HIV-1–infected individual, that… 
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