Rather rule than exception? How to evaluate the relevance of dual protein targeting to mitochondria and chloroplasts

@article{Sharma2018RatherRT,
  title={Rather rule than exception? How to evaluate the relevance of dual protein targeting to mitochondria and chloroplasts},
  author={Mayank Sharma and Bationa Bennewitz and Ralf B Kl{\"o}sgen},
  journal={Photosynthesis Research},
  year={2018},
  volume={138},
  pages={335-343}
}
Dual targeting of a nuclearly encoded protein into two different cell organelles is an exceptional event in eukaryotic cells. Yet, the frequency of such dual targeting is remarkably high in case of mitochondria and chloroplasts, the two endosymbiotic organelles of plant cells. In most instances, it is mediated by “ambiguous” transit peptides, which recognize both organelles as the target. A number of different approaches including in silico, in organello as well as both transient and stable in… Expand
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