Rates of antifungal resistance among Spanish clinical isolates of Cryptococcus neoformans var. neoformans.

@article{Perkins2005RatesOA,
  title={Rates of antifungal resistance among Spanish clinical isolates of Cryptococcus neoformans var. neoformans.},
  author={Alexander Perkins and Alicia G{\'o}mez-L{\'o}pez and Emilia Mellado and Juan Lu{\'i}s Rodr{\'i}guez-Tudela and Manuel Cuenca-Estrella},
  journal={The Journal of antimicrobial chemotherapy},
  year={2005},
  volume={56 6},
  pages={1144-7}
}
OBJECTIVES Activities in vitro of six antifungal agents were tested against a collection of 317 Cryptococcus neoformans var. neoformans clinical isolates. METHODS The procedure described in document 7.1 by the European Committee on Antibiotic Susceptibility Testing with minor modifications was employed. RESULTS Amphotericin B, itraconazole, voriconazole and ravuconazole exhibited a potent activity with geometric mean (GM) MICs under 0.26 mg/L. The GM MIC of flucytosine was 7.33 mg/L and… CONTINUE READING

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