Rates of Acquisition of Pneumococcal Colonization and Transmission Probabilities, by Serotype, Among Newborn Infants in Kilifi District, Kenya

@inproceedings{Tigoi2012RatesOA,
  title={Rates of Acquisition of Pneumococcal Colonization and Transmission Probabilities, by Serotype, Among Newborn Infants in Kilifi District, Kenya},
  author={Caroline C. Tigoi and Hellen Gatakaa and A. Hoseini Karani and Daisy Mugo and Stella Kungu and Eva Wanjiru and Jane Jomo and Robert Musyimi and J. O. Ojal and Nina E. Glass and Osman A. Abdullahi and J Anthony G Scott},
  booktitle={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2012}
}
BACKGROUND Herd protection and serotype replacement disease following introduction of pneumococcal conjugate vaccine (PCV) are attributable to the vaccine's impact on colonization. Prior to vaccine introduction in Kenya, we did an epidemiological study to estimate the rate of pneumococcal acquisition, by serotype, in an uncolonized population. METHODS Nasopharyngeal swab specimens were taken from newborns aged ≤ 7 days and weekly thereafter for 13 weeks. Parents, and siblings aged <10 years… CONTINUE READING
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