Rate of gas exchange in the middle ear of guinea pigs.

  title={Rate of gas exchange in the middle ear of guinea pigs.},
  author={H Mover-Lev and Jacob Sad{\'e} and Amos Ar},
  journal={The Annals of otology, rhinology, and laryngology},
  volume={107 3},
Gas exchange between blood in the middle ear (ME) mucosa and ambient ME gas may be limited by diffusion through tissue or blood perfusion. In order to study the limiting factors in ME gas exchange, a hole was drilled in the bulla of 14 anesthetized guinea pigs through which a mass spectrometer probe was inserted and sealed in place. The rate at which oxygen (O2), carbon dioxide (CO2), nitrogen, and argon concentrations changed toward their steady state values was recorded. From the exponential… CONTINUE READING