Rate control with ivabradine: angina pectoris and beyond.

@article{Parakh2011RateCW,
  title={Rate control with ivabradine: angina pectoris and beyond.},
  author={Neeraj Parakh and Balram Bhargava},
  journal={American journal of cardiovascular drugs : drugs, devices, and other interventions},
  year={2011},
  volume={11 1},
  pages={1-12}
}
The importance of heart rate in human health and disease has been well known to clinicians for quite some time. Recent epidemiologic studies have further strengthened this concept. Modulation of heart rate by pharmacologic as well as non-pharmacologic means has affected cardiovascular mortality and morbidity in various trials and observational studies. Conventional rate-control agents, such as β-adrenoceptor antagonists (β-blockers), calcium channel blockers, and digoxin, have contributed… CONTINUE READING

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