Rate constants of agonist binding to muscarinic receptors in rat brain medulla. Evaluation by competition kinetics.

Abstract

The method of competition kinetics, which measures the binding kinetics of an unlabeled ligand through its effect on the binding kinetics of a labeled ligand, was employed to investigate the kinetics of muscarinic agonist binding to rat brain medulla pons homogenates. The agonists studied were acetylcholine, carbamylcholine, and oxotremorine, with N-methyl… (More)

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@article{Schreiber1985RateCO, title={Rate constants of agonist binding to muscarinic receptors in rat brain medulla. Evaluation by competition kinetics.}, author={Gerhard Schreiber and Yoav I. Henis and Mordechai Sokolovsky}, journal={The Journal of biological chemistry}, year={1985}, volume={260 15}, pages={8795-802} }