Rat vs. rabbit ventricle: Ca flux and intracellular Na assessed by ion-selective microelectrodes.

@article{Shattock1989RatVR,
  title={Rat vs. rabbit ventricle: Ca flux and intracellular Na assessed by ion-selective microelectrodes.},
  author={Michael J. Shattock and Donald M. Bers},
  journal={The American journal of physiology},
  year={1989},
  volume={256 4 Pt 1},
  pages={C813-22}
}
Trans sarcolemmal Ca movements in rabbit and rat ventricular muscle were compared using extracellular double-barreled Ca-selective microelectrodes. In rabbit ventricle, steady-state twitches were associated with transient extracellular Ca (Cao) depletions, indicative of Ca uptake during the twitch. In contrast, steady-state twitches in rat ventricle were associated with net cellular Ca extrusion. Rest periods in rabbit ventricle lead to a net loss of cell Ca and resumption of stimulation… CONTINUE READING
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