Rat retinal tissue releases a vasorelaxing factor.

  title={Rat retinal tissue releases a vasorelaxing factor.},
  author={Koen Boussery and Christophe Delaey and Johan Van de Voorde},
  journal={Investigative ophthalmology & visual science},
  volume={43 10},
PURPOSE To investigate whether the retina of the rat exerts a vasodilatory influence by the release of a relaxing factor and to characterize the retinal relaxing factor (RRF). METHODS The relaxing influence of the rat retina was investigated by placing the retina in close proximity with a precontracted isolated rat carotid artery ring segment, mounted for isometric tension measurements. RESULTS Application of rat retina relaxed the artery in a reliable and reproducible way. The nitric oxide… CONTINUE READING