Rat prolactinoma cell growth regulation by epidermal growth factor receptor ligands.

@article{Vlotides2008RatPC,
  title={Rat prolactinoma cell growth regulation by epidermal growth factor receptor ligands.},
  author={George Vlotides and Emily Siegel and Ines Donangelo and Shiri Gutman and Song-guang Ren and Shlomo Melmed},
  journal={Cancer research},
  year={2008},
  volume={68 15},
  pages={6377-86}
}
Epidermal growth factor (EGF) regulates pituitary development, hormone synthesis, and cell proliferation. Although ErbB receptor family members are expressed in pituitary tumors, the effects of EGF signaling on pituitary tumors are not known. Immunoprecipitation and Western blot confirmed EGF receptor (EGFR) and p185(c-neu) protein expression in GH3 lacto… CONTINUE READING