Rat olfactory bulb and epithelium UDP-glucuronosyltransferase 2A1 (UGT2A1) expression: in situ mRNA localization and quantitative analysis.

@article{Heydel2001RatOB,
  title={Rat olfactory bulb and epithelium UDP-glucuronosyltransferase 2A1 (UGT2A1) expression: in situ mRNA localization and quantitative analysis.},
  author={J. M. Heydel and S{\'e}verine Leclerc and Pascal Bernard and H{\'e}l{\`e}ne Pelczar and Daniela Gradinaru and Jacques Magdalou and Alain Minn and Yves Artur and Herv{\'e} Goudonnet},
  journal={Brain research. Molecular brain research},
  year={2001},
  volume={90 1},
  pages={83-92}
}
UDP-glucuronosyltransferases (UGTs) form a multigenic family of enzymes involved in the biotransformation and elimination of numerous endo- and xenobiotic compounds. Beside the diverse UGT isoforms present in the liver as well as in other tissues, the UGT2A1 isoform, also called olfactory UGT, was initially thought to be expressed in the nasal epithelium only. In this work, we demonstrate the UGT2A1 mRNA expression in the olfactory bulb, using in situ hybridization and quantitative reverse… CONTINUE READING

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