Rat models of upper extremity impairment in stroke.

  title={Rat models of upper extremity impairment in stroke.},
  author={Jeffrey A. Kleim and Jeffery A Boychuk and DeAnna L Adkins},
  journal={ILAR journal},
  volume={48 4},
Stroke remains the leading cause of adult disability, with upper extremity motor impairments being the most prominent functional deficit in surviving stroke victims. The development of animal models of upper extremity dysfunction after stroke has enabled investigators to examine the neural mechanisms underlying rehabilitation-dependent motor recovery as well as the efficacy of various adjuvant therapies for enhancing recovery. Much of this research has focused on rat models of forelimb motor… CONTINUE READING