Rat lung tissue is a site of alpha 1-proteinase inhibitor synthesis: evidence by cell-free translation.

@article{Budek1984RatLT,
  title={Rat lung tissue is a site of alpha 1-proteinase inhibitor synthesis: evidence by cell-free translation.},
  author={W Budek and P B{\"u}nning and Peter Claus Heinrich},
  journal={Biochemical and biophysical research communications},
  year={1984},
  volume={122 1},
  pages={394-400}
}
Poly(A) +RNA isolated from lungs of normal rats and of rats suffering from experimental inflammation was translated in a cell-free translation mixture from rabbit reticulocytes. The translation products were immunoprecipitated with specific antisera against alpha 1-proteinase inhibitor and alpha 2-macroglobulin. Comparable levels of mRNA for alpha 1-proteinase inhibitor were found in rat lung tissue from control and experimentally inflamed animals. alpha 2-Macroglobulin mRNA could not be… CONTINUE READING