Rat liver mitochondrial dysfunction by addition of copper(II) or iron(III) ions.

Abstract

Increased copper (Cu) and iron (Fe) levels in liver and brain are associated to oxidative stress and damage with increased phospholipid oxidation process. The aim of this work was to assess the toxic effects of Cu2+ and Fe3+ addition to rat liver mitochondria by determining mitochondrial respiration in states 3 (active respiration) and 4 (resting… (More)
DOI: 10.1016/j.jinorgbio.2016.10.009

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