Rat liver clone-9 cells in culture as a model for screening hepatotoxic potential of food-related products: hepatotoxicity of deoxynivalenol.

@article{Sahu2008RatLC,
  title={Rat liver clone-9 cells in culture as a model for screening hepatotoxic potential of food-related products: hepatotoxicity of deoxynivalenol.},
  author={Saura C. Sahu and Larry H Garthoff and Martin G. Robl and Stuart J. Chirtel and Dennis I Ruggles and Thomas J. Flynn and Thomas Joseph Sobotka},
  journal={Journal of applied toxicology : JAT},
  year={2008},
  volume={28 6},
  pages={765-72}
}
Deoxynivalenol (DON) is a mycotoxin food contaminant found in several cereal grains. The literature on the liver toxicity of DON in vivo is conflicting and does not clearly characterize its hepatotoxic effects. Cultured rat liver clone-9 cells were used as a model to assess the hepatotoxic potential of DON. The cell cultures, seeded onto 96-well plates… CONTINUE READING