Rat liver cholesterol 7 alpha-hydroxylase. Pretranslational regulation for circadian rhythm.

@article{Noshiro1990RatLC,
  title={Rat liver cholesterol 7 alpha-hydroxylase. Pretranslational regulation for circadian rhythm.},
  author={Mitsuhide Noshiro and Masazumi Nishimoto and Kunio Okuda},
  journal={The Journal of biological chemistry},
  year={1990},
  volume={265 17},
  pages={
          10036-41
        }
}
A complete cDNA encoding cholesterol 7 alpha-monooxygenase (EC 1.14.13.17) which had been isolated from rat liver cDNA libraries by using specific antibodies to the enzyme (Noshiro, M., Nishimoto, M., and Okuda, K. (1989) FEBS Lett. 257, 97-100) was totally sequenced. The cDNA contained a 1,509-base pair open reading frame encoding 503 amino acid residues (Mr = 56,880) and an unusually long 3'-untranslated region rich in AT sequence in the total length of 3,545 base pairs. The predicted amino… CONTINUE READING

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