Rat lens gamma-crystallins. Characterization of the six gene products and their spatial and temporal distribution resulting from differential synthesis.

@article{Siezen1988RatLG,
  title={Rat lens gamma-crystallins. Characterization of the six gene products and their spatial and temporal distribution resulting from differential synthesis.},
  author={Roland J. Siezen and Eleanor Wu and E D Kaplan and J. Arthur Thomson and George B. Benedek},
  journal={Journal of molecular biology},
  year={1988},
  volume={199 3},
  pages={475-90}
}
We have isolated, purified and characterized six individual gamma-crystallin polypeptides present in the rat lens. Comparison of their amino acid compositions with the known structure of the six gamma-crystallin genes permits a one-to-one correspondence to be made between each protein synthesized and the encoding gene. This demonstrates that each of the six… CONTINUE READING