Rat kidney MAP17 induces cotransport of Na-mannose and Na-glucose in Xenopus laevis oocytes.

@article{Blasco2003RatKM,
  title={Rat kidney MAP17 induces cotransport of Na-mannose and Na-glucose in Xenopus laevis oocytes.},
  author={Tatiana Blasco and Jos{\'e} J. Aramayona and Ana Isabel Calvo Alcalde and Julia Catal{\'a}n and M Arraiza Sarasa and V{\'i}ctor Sorribas},
  journal={American journal of physiology. Renal physiology},
  year={2003},
  volume={285 4},
  pages={F799-810}
}
Renal reabsorption is the main mechanism that controls mannose homeostasis. This takes place through a specific Na-coupled uphill transport system, the molecular identity of which is unknown. We prepared and screened a size-selected rat kidney cortex cDNA library through the expression of mannose transport in Xenopus laevis oocytes. We have identified a membrane protein that induces high-affinity and specific Na-dependent transport of d-mannose and d-glucose in X. laevis oocytes, most likely… CONTINUE READING
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MAP17 is part of a proximal tubular apical complex containing Na/Pi-cotransporter NaPi-IIa and the PDZ protein NaPi-Cap1

  • S Pribanic, N Hernando, +4 authors H. Murer
  • J Am Soc Nephrol 13: 483a,
  • 2002
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