Rat follistatin: ontogeny of steady-state mRNA levels in different tissues predicts organ-specific functions.

@article{Michel1991RatFO,
  title={Rat follistatin: ontogeny of steady-state mRNA levels in different tissues predicts organ-specific functions.},
  author={Uwe Michel and Anjana Rao and Jock K. Findlay},
  journal={Biochemical and biophysical research communications},
  year={1991},
  volume={180 1},
  pages={223-30}
}
Follistatin (FS), a monomeric glycoprotein which specifically binds activin, is expressed in many tissues. This study investigated 1) the ontogeny of the steady-state FS mRNA levels in different extragonadal tissues and 2) whether the ratio of the differential splicing products, FS 344 or its carboxy-truncated form FS 317, is changed during postnatal development. Whereas the levels of FS mRNA 344 in the kidney showed a profound increase from the day of birth to adulthood, the levels in the… CONTINUE READING

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