Rat dopaminergic function in the retina during aging.


Parameters of dopaminergic transmission were studied in the retina of mature (3-4 months) and aged (23-24 months) rats. In the retina of senescent rats were found significantly higher dihydroxyphenylacetic acid (DOPAC) levels and a higher number of (3H-)spiroperidol binding sites. We detected also an increase of (3H)- methionine-enkephalin binding sites. The changes in the density of (3H)-spiroperidol and (3H)-Metenkephalin binding sites in the retina are opposite to those observed in the brain of aged rats.

Cite this paper

@article{Riccardi1981RatDF, title={Rat dopaminergic function in the retina during aging.}, author={Federica Riccardi and Vito Covelli and Pier Franco Spano and Stefano Govoni and Marco Trabucchi}, journal={Neurobiology of aging}, year={1981}, volume={2 3}, pages={229-31} }