Rat diaphragm during postnatal development. II. Resistance to low- and high-frequency fatigue.

@article{Fratacci1996RatDD,
  title={Rat diaphragm during postnatal development. II. Resistance to low- and high-frequency fatigue.},
  author={M D Fratacci and Micheline Levame and A. Rauss and G. Atlan},
  journal={Reproduction, fertility, and development},
  year={1996},
  volume={8 3},
  pages={399-407}
}
The effects on the rat diaphragm of fatigue induced by low- and high-frequency stimulation (at 5 Hz for 1.5 min and 75 Hz for 1 min) were examined during postnatal development. Experiments were performed on isolated costal diaphragm strips. Before stimulation, twitch contraction time and half relaxation time were longest in the neonate and decreased significantly between weeks 1 and 6. Correspondingly, the specific twitch tension (corrected for cross-sectional area) increased progressively with… CONTINUE READING

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